The 2026 Million Dollar Bike Ride takes place Saturday, June 13th. Check the MDBR site for more information and to sign up. ENDD director Ben Prosser will be riding with Lulu’s Crew, the team he and his spouse, Erin, created in honor of their own daughter, Lucy, who was born with STXBP1. You’re welcome to join them or […]
Emily Scarborough’s work, “Microtubule dynamics control the direction of cardiomyocyte growth,” was published in Science! Unexpectedly, this work uncovered how the heart uses microtubule stability as an upstream effector to enact two unique mechanisms to grow in either width or length. We are hopeful that this model reveals important generals fundamentals of cardiac growth.
Keita Uchida’s paper “mTORC1 and nuclear ERK spatially control translation in cardiomyocytes through 4EBP1 phosphorylation” has been published in Science Signaling…and was selected for the cover art! Excellent work, Keita!
Alex Felix has won CURE Epilepsy’s Taking Flight Award to advance his work on “Fine-tuning the 3’UTR as a novel therapeutic strategy for genetic Developmental and Epileptic Encephalopathies.”
September 2025: Katey Stone was awarded a Ruth L. Kirschstein National Research Service Award (F31 grant) from the National Heart, Lung, and Blood Institute for her project, “Investigating the protective role of stress granules in the heart.” Way to go!
Daria is now an assistant professor with her own lab at the Technion – Israel Institute of Technology, plus she’s first author on a paper that comes out of work begun in Ben’s lab: “Microtubule forces drive nuclear damage in LMNA cardiomyopathy,” just published in Nature Cardiovascular Research.
Yohei Yamauchi joined us as a visiting scholar from Japan. Read more about Yohei and our other lab members on our Team page.
Keita Uchida was awarded an American Heart Association grant to support his work on “Spatial Control Of Anabolism And Catabolism By Mtorc1 In The Heart.” This Career Development Award will help Keita establish his independent lab.
In this piece in Current Problems in Pediatric and Adolescent Health Care, “Accelerating therapeutic development and clinical trial readiness for STXBP1 and SYNGAP1 disorders,” Nick, Ben, and Mike Boland provide an overview of the disorders’ clinical features and the current understanding of pathogenic mechanisms and therapeutic development.
