Microtubule dynamics control the direction of cardiomyocyte growth. Scarborough EA, Randell R, Uchida K, Stone KR, Margulies KB, Prosser BL. Science. 2026 Apr 23:eadz1970. doi: 10.1126/science.adz1970. Epub ahead of print. PMID: 42024777.
mTORC1 and nuclear ERK spatially control translation in cardiomyocytes through 4EBP1 phosphorylation. Uchida K, Scarborough EA, Pruzinsky E, Stone KR, Hartman H, Kelly DP, Edwards JJ, Kehat I, Prosser BL. Sci Signal. 2026 Apr 21;19(934):eadu5769. doi: 10.1126/scisignal.adu5769. Epub 2026 Apr 21. PMID: 42013184.
Active transport of tRNAs facilitates distributed protein synthesis. Petrosino J, Courelli V, Uchida K, Bond C, Cooperman B, Bogush A, Lakadamyali M, Prosser BL. bioRxiv. 2026.01.26.698744. PMID: 41659417. PMCID: PMC12874057. doi:10.64898/2026.01.26.698744.
Integrated Stress Response Potentiates Ponatinib-Induced Cardiotoxicity. Yan G, Han Z, Kwon Y, Jousma J, Nukala SB, Prosser BL, Du X, Pinho S, Ong SB, Lee WH, Ong SG. Circ Res. 2024 Mar 1;134(5):482-501. PMID:38323474. doi: 10.1161/CIRCRESAHA.123.323683
Mapping PTBP2 binding in human brain identifies SYNGAP1 as a target for therapeutic splice switching. Dawicki-McKenna JM, Felix AJ, Waxman EA, Cheng C, Amado DA, Ranum PT, Bogush A, Dungan LV, Maguire JA, Gagne AL, Heller EA, French DL, Davidson BL, Prosser BL. Nat Commun. 2023 May 6;14(1):2628. PMID: 37149717. doi: 10.1038/s41467-023-38273-3.
Cardiomyocyte Microtubules: Control of Mechanics, Transport, and Remodeling. Uchida K, Scarborough EA, Prosser BL. Annu Rev Physiol. 2022 Feb 10;84:257-283. doi: 10.1146/annurev-physiol-062421-040656. Epub 2021 Oct 6. PMID: 34614374. Review.
Microtubules orchestrate local translation to enable cardiac growth. Scarborough EA, Uchida K, Vogel M, Erlitzki N, Iyer M, Phyo SA, Bogush A, Kehat I, Prosser BL. Nat Commun. 2021 Mar 11;12(1):1547. PMID: 33707436. doi: 10.1038/s41467-021-21685-4.
Cardiac microtubules in health and heart disease. Caporizzo MA, Chen CY, Prosser BL. Exp Biol Med. 2019 Nov;244(15):1255-1272. Epub 2019 Aug 9. PMID: 31398994. doi: 10.1177/1535370219868960. Review.